Gum Disease Bacteria Linked to Calcification and Damage of Heart Valves
Research is exploring a potential link between oral health and cardiovascular function, suggesting that bacteria found in gum disease may contribute to heart valve problems. Specifically, harmful bacteria are implicated in driving calcific aortic valve stenosis by initiating an inflammatory response. This mechanism involves the bacteria colonizing the heart's aortic valve and activating inflammatory proteins, such as IL-1β. Studies investigating both mouse and human cardiac tissue have found evidence supporting this connection, indicating that periodontitis could be a hidden risk factor for serious heart valve conditions.
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